Corrective shampoos containing cadmium sulfide



Patented Jan. 1, 1963 3,071,514 CORRECTIVE SHAMPQGd CQNTAINENG CADMHUM SULFFDE Robert A. Fhillips and .iohn W. Lee, indianapoiis, ind, assignors, by rnesnc assignments, to The Dow Chemical Company, Midland, Mich a corporation of Belaware No Drawing. Filed Sept. 1, 1955, No. 532,119 3 Claims. (Cl. 167-437} This invention relates to corrective shampoos containing cadmium sulfide, methods of preparing said shampoos and their use for the control of pruritis, and non-specific and seborrheic dermatoses.

An object of this invention is to provide a corrective shampoo comprising cadmium sulfide in an aqueous medium in association with a detergent foaming base.

Another object of this invention is the provision of a corrective shampoo comprising an aqueous medium containing cadmium sulfide, silicon dioxide and a detergent.

Still another object of this invention is the provision of a method for producing a corrective shampoo containing cadmium sulfide, silicon dioxide and a detergent in an aqueous medium.

A further object of this invention is the provision of a method for controlling pruritis, and non-specific and seborrheic dermatoses by using a corrective shampoo containing cadmium sulfide and a detergent in an aqueous medium.

In accordance with the present invention, it has been discovered that aqueous shampoos containing cadmium sulfide, and a detergent are useful for treating a wide variety of skin abnormalities such as, for example, nonspecific and seborrheic dermatoses in cats and dogs and dandruff in humans. These beneficial results were entirely unexpected since cadmium sulfide is an extremely water insoluble substance. It appears, however, that in spite of this insolubility, cadmium sulfide when properly brought into contact with these abnormal skin conditions will bring about a very desirable corrective effect without producing undesirable toxic effects. We believe that the beneficial effects may be due in part at least to the intimate association of cadmium sulfide with silicon dioxide in the aqueous detergent base, which permits a uniform contact with the afiected skin areas, hair follicles, and hairs. Another important property is the ease and completeness with which the cadmium sulfide can be removed from the treated areas after remaining in contact therewith for 10 or more minutes by merely rinsing in water.

In producing compositions in accordance with our invention, cadmium sulfide is suspended in an aqueous medium containing a detergent such as, for example, triethanolamine lauryl sulfate. In a preferred method, the cadmium sulfide is first intimately mixed with a silicon dioxide product such as Cab-O-Sil (Cabot Company, Boston, Massachusetts), ranging in size from about 0.01 to 0.1 of a micron. In addition to these three preferred basic ingredients, auxiliary substances such as gums, foamers, hair conditioners, and odors may be employed. The following specific example will serve to illustrate suitable corrective shampoos and their method of preparation.

2 lbs. 8 oz. of silicon dioxide (Cab-O-Sil) are milled with 1 lb. 12 oz. of cadmium sulfide in gallons of water. After a smooth mixture has been obtained, 13 oz. of sodium alginate are added and again milled until a smooth mixture is obtained. Then 41 lbs. 12 oz. of 44% triethanolamine lauryl sulfate solution and 8 lbs. 8 oz. of diethanolamide of lauric acid are added and thoroughly mixed. 3 fiuid ounces of an odor, Neutrosccnt (Fritzsche Company), or other suitable perfumed liquid and enough water to make a total of 20 gallons are added. The final shampoo contains cadmium sulfide 1.0% w./v. in a detergent base.

In the foregoing specific example, the particular detergent employed may be replaced by any suitable detergent such as, for example, alkyl aryl sulfonates, fatty acid soaps, coconut oil soaps, polyalkylene alkyl phenols, sodium aliryl sarcosinates, sodium sulfosuccinic esters and dodecyl B alanine.

Similarly, the sodium alginate may be replaced by any suitable gum such as, for example, guar, methyl cellulose, Veegum (Vanderbilt Co.) and tragacanth.

The cadmium sulfide content of our corrective shampoos can be varied as desired. We prefer concentrations ranging from about 1% to about 2.5%. Cab-O-Sil is a preferred silicon dioxide product in our formulation, and the preferred concentrations range from about 1 to about 3%. However, Cab-O-Sil may be replaced by other silicon dioxides such as, for example, Ludox (Du Pont Company) and Santocel (Monsanto Company). The detergent content of our shampoo varies from about 5 to about 15%; the gum from about 1 to about 2%; the hair conditioner from about 2.5 to about 10%; and the odor neutralizer from about 0.01 to about 0.2%. The expression aqueous medium as employed in this specification and in the claims does not preclude the addition of reasonable quantities of water-miscible, non-toxic liquid adjuvants such as, for example, 2 to 10% of the following: ethyl alcohol, isopropyl alcohol, propylene glycol, monoethyl ether of diethylene glycol or similar substances.

A process for using our shampoo for correcting abnormal skin conditions comprises applying it to an infected hairy area, allowing it to remain for a period of at least 10 minutes and then rinsing with Water to effect removal of the shampoo ingredients.

We claim:

1. A corrective shampoo composition comprising an aqueous suspension containing cadmium sulfide 1 to 2.5%, silicon dioxide 1 to 3%, a foaming detergent 5 to 15% and a water dispersible gum 1 to 2%.

2. A process for correcting abnormal skin conditions which consists in applying a corrective shampoo, comprising cadmium sulfide, silicon dioxide and. a detergent in an aqueous medium, to an infected hairy area, allowing said shampoo to remain for a period of at least 10 minutes and rinsing with water to remove said shampoo ingredients.

3. A process for correcting abnormal skin conditions which consists in applying a corrective shampoo comprising cadmium sulfide and a detergent in an aqueous medium to an infected hairy area, allowing said shampoo to remain for a period of at least ten minutes and rinsing with water to remove said shampoo ingredients.

References Cited in the file of this patent UNITED STATES PATENTS 2,149,249 Nitsche Feb. 28, 1939 2,314,125 Coca Mar. 16, 1943 2,383,990 Quisling Sept. 4, 1945 2,694,669 Baldwin et al Nov. 16, 1954 2,696,455 Blair Dec. 7, 1954 FOREIGN PATENTS 523,107 Great Britain lluly 5, 1940 831,736 Germany Feb. 18, 1952 OTHER REFERENCES Redgrove Hair-Dyes and Hair Dyeing Chemistry and Technique Chemical Publishing Co., New York, 1939,. pp. 52-53.

].A.M.A., vol. 139, No. 13, March 26, 1949, pp. 840- 844. 

1. A CORECTIVE SHAMPOO COMPOSITION COMPRISING AN AQUEOUS SUSPENSION CONTAINING CADMIUM SULFIDE 1 TO 2.5%, SILICON DIOXIDE 1 TO 3%, A FOAMING DETERGENT 5 TO 15% AND A WATER DISPERSIBLE GUM 1 TO 2%. 